This can be "fixed" by removing everything from the appropriate ScreenEdge section in your mouse config. In the example case comment out everything in ScreenEdge{Bottom{}}.
Should a non-relevant EnterMoving or ButtonRelease disable the simple "left-click" or in fact anything else that isn't defined in the mouse config, I don't know, but it seems like a decent drawback when one is using the EdgeIndent feature.
You need to delete ScreenEdge { Down {} } stuff and it should be solved man ;).